Dysphagia optimised imrt
WebDec 1, 2024 · Dysphagia-optimised IMRT resulted in a significantly higher mean MDADI score at 12 months post-radiotherapy (78 versus 70; P = 0.02) with no apparent … WebNov 1, 2015 · In this review, we discuss the swallowing structures responsible for functional impairment, analyse the studies that have explored the dose–response relationship between these critical structures and late dysphagia, and consider the merits of reported dysphagia-optimised IMRT (Do-IMRT) approaches, thus far.
Dysphagia optimised imrt
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Websparing strategies. The aim of Dysphagia/Aspiration at risk structures (DARS) trial is to determine whether reducing the dose to the pharyngeal constrictors with dysphagia-optimised intensity- modulated radiotherapy (Do-IMRT) will lead to an improvement in long- term swallowing function without having any detrimental impact on disease- WebFeb 24, 2024 · The preferential sparing achievable with intensity-modulated radiotherapy (IMRT) of key swallowing structures implicated in post-radiation dysfunction, such as the pharyngeal constrictor muscles (PCM), has generated significant research into toxicity-mitigating strategies. The lack of randomised evidence, however, means that there …
WebMar 18, 2024 · Petkar I, Rooney K, Roe JWG, et al. DARs: a phase III randomised multicentre study of dysphagia-optimised intensity modulated radiotherapy (do-IMRT) versus standard intensity-modulated radiotherapy (S-IMRT) in head and neck cancer. BMC Cancer. 2016;16:1–10. Article Google Scholar WebJan 27, 2024 · But half have a modified type of IMRT (called dysphagia optimised IMRT or Do-IMRT). This is to reduce the radiation dose to the muscles that control swallowing. The aim of the study is to compare the people having the Do-IMRT with those having standard IMRT treatment. This is to find out if modifying the IMRT will improve swallowing after ...
WebDysphagia is a distressing symptom during and after radiotherapy treatment in head and neck cancer (HNC) patients. The objective of this prospective study was to investigate … WebJul 1, 2024 · Increasingly, there is a focus to establish dysphagia-optimised IMRT (Do-IMRT) strategies [18], which could translate into improved long-term symptom burden …
WebSep 9, 2024 · DARS (ISRCTN:25458988) tested if using DO-IMRT to reduce RT dose to the dysphagia/aspiration related structures (DARS) improved swallowing function compared to S-IMRT. Materials and Methods Patients with T1-4, N0-3, M0 OPC/HPC were randomised 1:1 to S-IMRT (65 Gray (Gy)/30 fractions (f) to primary & nodal tumour; 54 Gy/ 30f to …
WebDec 1, 2024 · Dysphagia-optimised IMRT resulted in a significantly higher mean MDADI score at 12 months post-radiotherapy (78 versus 70; P = 0.02) with no apparent detriment to local control [21, 22]. Studies such as PARSPORT and DARS constitute a structured, evidence-based approach to the introduction of new radiotherapy technology and … incidence of gastric cancer ukWebFeb 24, 2024 · The preferential sparing achievable with intensity-modulated radiotherapy (IMRT) of key swallowing structures implicated in post-radiation dysfunction, such as the … inconsiderate parking noticesWebMay 25, 2024 · Methods: Patients with T1-4, N0-3, M0 OPC/HPC were randomised 1:1 to S-IMRT (65 Gray (Gy)/30 fractions (f) to primary & nodal tumour; 54Gy/30f to remaining pharyngeal subsite & nodal areas at risk of microscopic disease) or Do-IMRT. incidence of gastroparesisWebThis study examined knowledge and practices of speech pathologists (SPs) and radiation therapists (RTs) regarding plan optimisation for head and neck cancer patients, and the potential impacts on swallowing function. This study examined knowledge and practices of speech pathologists (SPs) and radiation therapists (RTs) regarding plan optimisation for … inconsiderate parking ukWebsparing strategies. The aim of Dysphagia/Aspiration at risk structures (DARS) trial is to determine whether reducing the dose to the pharyngeal constrictors with dysphagia … inconsiderate parking lawWebIMRT had a statistically significant advantage over 3D CRT, in terms of V30 (p=0.051), V50 (p=0.002), V60 (p=0.002), and D80 (p=0.023) for the swallowing structures taken together. ... Further prospective studies are required to confirm these findings. Dysphagia-optimised IMRT is needed to improve swallowing status and quality of life in these ... incidence of gender dysphoriaWebingly, there is a focus to establish dysphagia-optimised IMRT (Do-IMRT) strategies [18], which could translate into improved long-term symptom burden outcomes for pharyngeal cancer patients by reducing dose to critical swallowing structures. Refinements to existing technology, in the form of arc-based IMRT and adaptive radiotherapy, inconsiderate of your time