Cisplatin induced tma
WebBoth gemcitabine and cisplatin have been reported to cause drug-induced TMA [8–11]. Regarding drug-induced TMA due to gemcitabine, its incidence has been reported to range from 0.015 to 1.4% [12]. The risk increases with the dose of gemcitabine and with prolonged duration of treat- ment [12]. WebZurück zum Zitat Izzedine H, Isnard-Bagnis C, Launay-Vacher V, Mercadal L, Tostivint I, Rixe O et al (2006) Gemcitabine-induced thrombotic microangiopathy: a systematic review. Nephrol Dial Transplant 21(11):3038–3045 CrossRefPubMed Izzedine H, Isnard-Bagnis C, Launay-Vacher V, Mercadal L, Tostivint I, Rixe O et al (2006) Gemcitabine …
Cisplatin induced tma
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WebJan 11, 2024 · Cisplatin [cis-diamminedichloridoplatinum(II)] is a widely used chemotherapeutic drug in the treatment of various types of cancers, including testicular, bladder, ovarian, breast, head and neck, and small and non-small cell lung cancers. WebJan 11, 2024 · Cisplatin and other platinum(II) analogs are widely used in clinical practice as anti-cancer drugs for a wide range of tumors. The primary mechanism by which they …
WebApr 12, 2024 · Zurück zum Zitat Izzedine H et al. Gemcitabine-induced thrombotic microangiopathy: a systematic review. Nephrol Dial Transplant. 2006;21(11):3038–45. ... Zurück zum Zitat Gilbert RD et al. Cisplatin-induced haemolytic uraemic syndrome associated with a novel intronic mutation of treated with eculizumab. Clin Kidney J. … WebJun 28, 2016 · Thrombotic microangiopathies (TMA) are a group of disorders characterised by disseminated occlusive microvascular …
WebCisplatin is also sometimes used to treat head and neck cancer (including cancer of the mouth, lip, cheek, tongue, palate, throat, tonsils, and sinuses), lung cancer, cancer of the … WebPlatinum, the Synergistic Drug: From Clinical Evidence to Laboratory Suggestions.- Chemotherapy of Mammary Cancer with Anthracyclins and Alkylators.- The Pharmaceutical Stabilization of the Clinical Anticancer Drug Dach-Platinum-TMA (NSC271674).- A Clinical Study of Reduced Glutathione as a Protective Agent Against Cisplatin-Induced Toxicity.-
WebNov 10, 2008 · One drug commonly implicated in inducing TMA is the immunosuppressant cyclosporine A (CyA). CyA-induced TMA is seen often in transplant patients (solid or liquid), but also in patients treated for rheumatoid arthritis and uveitis. The mechanism is believed to be a dose-related toxicity.
WebDec 1, 2015 · In the kidney, TMA appears as endocapillary cell swelling, fibrin thrombi, platelet plugs, arterial intimal fibrosis, and membranoproliferation. Many chemotherapeutic agents, including mitomycin, bleomycin, cisplatin, and 5-fluorouracil, can induce TMA, but the precise pathophysiology is unknown. great lakes eatery dundee miWebApr 21, 2024 · Refer to UpToDate topics on cisplatin nephrotoxicity. Thrombotic microangiopathy: TMA (also sometimes called thrombotic thrombocytopenic purpura … floating water plantsWebSep 18, 2024 · National Center for Biotechnology Information floating water plants for fountainsWebApr 1, 2024 · Drug-induced TMA (DI-TMA) is a thrombotic microangiopathy (TMA) caused by certain drugs,usually managed by drug discontinuation and supportive measures. Data on the use of complement-inhibition with eculizumab in DI-TMA is scarce, and its benefit in cases of severe or refractory DI-TMA is unclear. great lakes ear nose throatWebSep 1, 2024 · Cisplatin-induced nephrotoxicity is dose-dependent and also increases with recurrent drug administration.19 In patients with thoracic malignancies (mostly NSCLC), … great lakes eateryWebApr 6, 2024 · Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy (TMA) characterized by the triad of ... cisplatin, bleomycin, and 5-FU, all of which have been shown to cause HUS [13]. ... Reese JA, Terrell DR, Vesely SK, George JN: Drug-induced thrombotic microangiopathy: a systematic review of published reports. Blood. 2015, … floating water plants near meWebNov 1, 2015 · Oxaliplatin, a third-generation platinum agent, has been reported to induce thrombocytopenia or hemolysis, although this appears to be through immune-mediated mechanisms.80, 81 A few cases of oxaliplatin-induced TMA have been reported, but this is a rare occurrence. 80, 82, 83, 84 Pegylated Liposomal Doxorubicin floating water plants indoor